The Structure of Testis Angiotensin-Converting Enzyme (tACE-g13) in Complex with the Inhibitor RXPA380
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Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.
Angiotensin I-converting enzyme (ACE) is a highly glycosylated type I integral membrane protein. A series of underglycosylated testicular ACE (tACE) glycoforms, lacking between one and five N-linked glycosylation sites, were used to assess the role of glycosylation in tACE processing, crystallization and enzyme activity. Whereas underglycosylated glycoforms showed differences in expression and ...
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